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NEOVIS TOTAL MULTI ophthalmic lubricating emulsion for eye instillation Bottle/15ml

Horus Pharma

NEOVIS TOTAL MULTI ophthalmic lubricating emulsion for eye instillation Bottle/15ml

CIP / EAN code: 3664490000086

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Product information

Find indications, dosage and precautions in the sections below.

Automatic English translation of the French VIDAL document. Original numerical values and units are retained, including decimal commas.

VIDAL
Parapharmacy
Update of 27/01/2026

CE NEOVIS® TOTAL / NEOVIS® TOTAL MULTI
lubricating ophthalmic emulsion without preservative

Forms and presentations 

Sterile hypo-osmolar lubricating emulsion without preservative for topical ophthalmic use: 
Neovis total: Box of 30 single-dose units of 0,4 ml (ACL 3401060210120).

Neovis total Multi: Multi-dose vial of 15 ml without preservative (EAN 3664490000086).

Composition 

Sodium hyaluronate (0,18 %), triglycerides and phospholipids, lipoic acid, hydroxypropylmethylcellulose, sodium citrate, sodium hydroxide, citric acid, sodium chloride and water for injectable preparation. Without preservative agent. The emulsion is hypo-osmolar.

Indications 

Neovis total and Neovis total Multi are indicated in adults for moderate to severe sensations of dry eye (no studies have been conducted in children).

Contraindications 

Do not use in case of hypersensitivity to any of the components.

Properties 

Neovis total and Neovis total Multi are emulsions that stabilise the tear film. Neovis total and Neovis total Multi contain sodium hyaluronate, a component naturally present in the eye, which helps protect and hydrate the ocular surface. Thanks to the physical properties of sodium hyaluronate, Neovis total and Neovis total Multi have a strong water-retention capacity and viscoelastic properties that allow the formation of a lubricating, homogeneous and protective film on the surface of the eye. In this way, it acts on the aqueous layer to hydrate and protect the ocular surface. Neovis total and Neovis total Multi are hypo-osmolar in order to compensate for the deleterious phenomena (inflammation) induced by the hyperosmolarity of tears in case of dry eye. Sodium hyaluronate also has mucomimetic properties allowing Neovis total and Neovis total Multi to promote anchoring of the tear film. They are without preservative and without surfactant in order to optimise local tolerance.

Directions for use 

Neovis total and Neovis total Multi are used by the ocular route.
Unless otherwise recommended, instil 1 to 2 drops as often as necessary. After instillation, a few spontaneous eyelid blinks will allow the emulsion to spread evenly over the ocular surface as a transparent and lasting film.
Wash hands thoroughly before proceeding with instillation.
Single-dose form:
Open the sachet and detach one single-dose unit from the strip, taking care to store the other single-dose units in the original packaging. Always shake the single-dose unit before instillation. Hold the single-dose unit vertically (cap head up) and turn the flat part completely to break the seal. The single-dose unit is open. Tilt the head backwards and position the tip of the single-dose unit above the eye. Gently pull the lower eyelid downwards with the index finger while looking upwards, then gently press the body of the single-dose unit until a drop of Neovis total is released. Unless otherwise recommended, instil 1 to 2 drops as often as necessary. After instillation, a few spontaneous eyelid blinks will allow the emulsion to spread evenly over the ocular surface as a transparent and lasting film.
Multidose form:
At first use, unscrew the cap after checking the integrity of the ring sealed to the cap. This tamper-evident ring breaks at the moment of first opening (characteristic sound). Always shake the vial before instillation. Unless otherwise recommended, instil 1 to 2 drops into the eye as often as necessary. Using the index finger, gently pull the lower eyelid downwards while looking upwards, then squeeze the vial to instil the drops. Avoid contact of the vial tip with the eye or eyelids. After instillation, a few spontaneous eyelid blinks will allow the emulsion to spread evenly over the ocular surface as a transparent and lasting film. Screw the vial back on using the protective cap after each use, making sure there is no residual drop on the tip; if necessary, shake it off with a sharp flick of the wrist.
Neovis total and Neovis total Multi are compatible with wearing contact lenses.

Precautions for use 

For external use only.

Do not swallow.

Avoid any contact of the tip of the opened single-dose unit or the tip of the vial with the hands, eye and eyelids (risk of microbial contamination).

If symptoms persist during use of Neovis total/Neovis total Multi, consult a doctor.

Keep out of the reach and sight of children.

Wash hands thoroughly before proceeding with instillation.

Always shake the single-dose unit or vial before instillation.

Single-dose form:
The single-dose unit must be discarded immediately after use and must not be kept for later instillation (risk of microbial contamination and loss of product performance). Do not use if the single-dose unit is damaged (risk of microbial contamination).
Multidose form:
Screw the vial back on using the protective cap after each use, making sure there is no residual drop on the tip; if necessary, shake it off with a sharp flick of the wrist. Do not use if the vial is damaged (risk of microbial contamination).
Interactions
When prescribing another eye drop, observe an interval of 15 minutes between instillations of the two eye drops (risk of altering the effect of the eye drops).
Adverse effects
In very rare cases, transient disturbances such as slight irritation of the conjunctiva, a foreign body sensation, redness or a burning sensation in the eye, as well as momentarily blurred vision may occur. If an undesirable effect persists or is not described in the leaflet, stop using the product and consult a doctor.

STORAGE CONDITIONS 

Store between 2 °C and 25 °C.
Do not use after the expiry date indicated on the box, the single-dose container or the bottle (risk of microbial contamination).
Use Neovis total Multi within 4 months after first opening (risk of contamination and loss of product performance).

ADMINISTRATIVE INFORMATION 

LPPR rate:
3,94 euros (Neovis total, 30 single-dose containers of 0,4 ml; LPPR code 1159257).
8,75 euros (Neovis total Multi, bottle of 15 ml; LPPR code 1100650).
Recommended price:15,80 euros (Neovis total: 30 single-dose containers of 0,4 ml).
Maximum retail selling price:12,14 euros (Neovis total Multi: bottle of 15 ml).
AAD service code.
Prescription by an ophthalmologist, after diagnosis of keratitis or dry keratoconjunctivitis, notably by a colorimetric test performed with a slit lamp, as third-line treatment after failure of low-viscosity artificial tears and gels. Under these conditions, the Neovis total and Neovis total Multi emulsions are not indicated in contact lens wearers.
Initial prescription may not exceed 6 months of treatment. Renewal authorised after ophthalmological examination.

Medical device, class IIb CE 0459.

HORUS PHARMA
22, Allée Camille-Muffat
INEDI 5. 06200 Nice
Tel: 04 93 19 54 03. Fax: 04 93 19 54 09
https://www.horus-pharma.com

Source: VIDAL · Updated on 11/11/2026. This information does not replace advice from a healthcare professional.