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HYLOVIS MULTI S ophtalm lubrifiante pour instillation oculaire Fl/15ml

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Find indications, dosage and precautions in the sections below.

Automatic English translation of the French VIDAL document. Original numerical values and units are retained, including decimal commas.

VIDAL
Parapharmacy
Update of the 05/08/2026

CE HYLOVIS®, HYLOVIS® MULTI 15 ocular solution
sodium hyaluronate at 0,18 %

Forms and presentations 

Sterile solution for topical ophthalmic use:  
  • Hylovis: Box of 20 single-dose units of 0,3 ml (ACL 3401046071189).
  • Hylovis Multi 15: Multidose vial of 15 ml without preservative (EAN 3760054330016).

Composition 

Sodium hyaluronate: 1,8 mg/ml; sodium, potassium, magnesium, calcium chlorides; disodium hydrogen phosphate; sodium citrate; water for injection. Without preservative agent. The solution is hypotonic.

Properties 

Hylovis and Hylovis Multi 15 contain hyaluronic acid, a natural polymer also present in the structures of the human eye. The particular physical characteristics of hyaluronic acid give Hylovis and Hylovis Multi 15 their important "viscoelastic" and water-retention properties. Hylovis and Hylovis Multi 15 thus form a stable film on the surface of the eye that is only slowly removed by blinking of the eyelids. Hylovis and Hylovis Multi 15 thus combine a prolonged effect with maximum comfort. Due to their particular composition, Hylovis and Hylovis Multi 15 are very well tolerated. They do not contain a preservative.

Indications 

Moderate and severe sensations of dry eye.

Directions for use 

Single-dose form:
  • Turn and detach the upper part to open.
  • Tilt the head back and position the tip of the bottle above the eye to be treated.
  • Pull the lower eyelid down with the index finger of one hand.
  • Squeeze the single-dose unit and a drop of Hylovis will flow out easily.
Unless otherwise recommended, instil 1 to 2 drop(s) of Hylovis into the eye as often as necessary.
A few blinks of the eyelids will ensure even distribution of the solution over the ocular surface as a transparent and lasting film.
 
Multidose form:
  • Remove the tamper-evident ring before the first administration.
  • Remove the protective cap.
  • Tilt the head back and position the tip of the bottle above the eye to be treated.
  • Pull the lower eyelid down with the index finger of one hand.
  • Squeeze the body of the vial and a drop of Hylovis Multi will flow out easily.
Unless otherwise recommended, instil 1 to 2 drop(s) of Hylovis Multi into the eye as often as necessary.
A few blinks of the eyelids will ensure even distribution of the solution over the ocular surface as a transparent and lasting film.
 
Hylovis and Hylovis Multi 15 may be used while wearing contact lenses, regardless of type (soft or rigid).

Contraindications 

Hypersensitivity to any of the components of the product.

Precautions for use 

If symptoms persist while using Hylovis or Hylovis Multi 15, consult a doctor.

Keep out of the reach of children.

  • Single-dose form:
    Do not touch the open part of the single-dose unit with your fingers and avoid direct contact with the eye. Do not use Hylovis if the single-dose unit is damaged. As Hylovis does not contain a preservative, do not reuse the contents of the single-dose unit after opening it.
  • Multi-dose form:
    Do not touch the tip of the opened bottle and do not touch the surface of the eye with the tip of the bottle. Replace the protective cap of Hylovis Multi 15 after use. Do not use Hylovis Multi 15 if the bottle is damaged. Hylovis Multi 15 may be used for up to 6 months after first use.

Store between + 2 °C and + 30 °C.

Adverse effects
In very rare cases, temporary disturbances such as irritation of the conjunctiva, a foreign body sensation, redness or a burning sensation of the eye, as well as momentarily blurred vision may occur.
Concomitant treatment with risk of interaction:
Do not administer Hylovis or Hylovis Multi 15 at the same time as other ophthalmic products or medicines, as they could alter their effects.

ADMINISTRATIVE INFORMATION 

LPPR rate:
2,91 euros (Hylovis: 20 single-dose units of 0,3 ml), LPPR code 1146190.
8,75 euros (Hylovis Multi 15: bottle of 15 ml), LPPR code 1130124.
Maximum retail selling price:12,14 euros (Hylovis Multi 15).

AAD service code.
 
Covered indication:
Symptomatic treatment of dry eye with keratitis or dry keratoconjunctivitis, as third-line therapy after failure of low-viscosity artificial tears and gels (carbomer type).
In this indication, the use of Hylovis and Hylovis Multi is not indicated in patients wearing contact lenses.
 
Prescribing and use conditions:
- prescription by an ophthalmologist after diagnosis of keratitis or dry keratoconjunctivitis, in particular by a colorimetric test performed with a slit lamp;
- initial prescription not to exceed 6 months of treatment. At the end of this period, reassessment, ideally by an ophthalmologist, for possible renewal of the prescription.

Medical device, class IIb CE 0123.
 
Manufacturer: TRB Chemedica AG, Otto-Lilienthal-Ring 26, 85622 Feldkirchen/München, Germany.

TRB CHEMEDICA SAS
ArchParc, ActiTech 4
60, avenue Marie-Curie
CS 40218. 74160 Archamps
Tel: 04 50 95 09 00
https://trbchemedica.fr/

Source: VIDAL · Updated on 10/11/2026. This information does not replace advice from a healthcare professional.