HEPARGITOL oral powder solution 10 sachet A + 10 sachet B

Compartment A

Sorbitol .....................................................................................................................................................................1,8450 g

Citric acid ..........................................................................................................................................................0,8780 g

per compartment

Compartment B

Arginine hydrochloride .........................................................................................................................................0,5000 g

Sorbitol .....................................................................................................................................................................1,5700 g

Anhydrous sodium sulfate ...................................................................................................................................0,0660 g

Sodium hydrogen phosphate .........................................................................................................................0,1190 g

per compartment

Excipients with known effect : sucrose, sodium

• Used in the symptomatic treatment of dyspeptic disorders.
• Adjunctive treatment of constipation.

Simultaneously empty the contents of both compartments of the sachet into half a glass of water and stir until completely dissolved.

• In the symptomatic treatment of dyspeptic disorders: take before meals or at the time of symptoms.
  • Adults: 2 to 4 bi-compartment sachets per day
  • Children over 5 years: 1 to 2 sachets per day
  • Children from 2 years to 5 years: 1 bi-compartment sachet per day or every other day.
• In the adjunctive treatment of constipation:
  • Adults: 2 sachets in the morning on an empty stomach

• Inflammatory organic colopathies (ulcerative colitis, Crohn's disease...), occlusive or subocclusive syndrome, abdominal pain syndromes of undetermined cause.
• Genetic fructose intolerance, rare metabolic disease.

Warning

Drug treatment of constipation is only an adjunct to hygienic-dietary treatment:

• enrichment of the diet with vegetable fibres and fluids;
• Advice on physical activity and rehabilitation of evacuation.

Prolonged use of a laxative is not recommended.

Precautions for use

• Do not use in case of obstruction of the bile ducts.
• In patients with colitis, avoid taking the medicine on an empty stomach and reduce the dosage.
• In case of a sodium-restricted diet, take into account in the daily ration 0,277 g of sodium per two-chamber sachet.
• In case of diabetes, take into account the presence of 0,500 g of sucrose per two-chamber sachet.

The data available to date do not suggest the existence of clinically significant interactions.

Given the available data, use in pregnant or breastfeeding women is possible.

Risk of diarrhoea and abdominal pain, particularly in subjects suffering from irritable colon or intestinal flatulence.

Risk of diarrhoea at high doses.

Pharmacotherapeutic class:

HEPATOBILIARY-TARGETED MEDICINE, OSMOTIC LAXATIVE.

Sorbitol stimulates the secretion of cholecystokinin-pancreozymin, which promotes contraction of the gallbladder and secretion of pancreatic juice.

It causes hyperhydration of the intestinal contents.

It accelerates intestinal transit through its osmotic laxative effect.

3 years

No special precautions for storage.

No special requirements.